Detalhe da pesquisa
1.
Human Monocytes Engage an Alternative Inflammasome Pathway.
Immunity
; 44(4): 833-46, 2016 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27037191
2.
K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria.
Immunity
; 45(4): 761-773, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27692612
3.
Prevention of the foreign body response to implantable medical devices by inflammasome inhibition.
Proc Natl Acad Sci U S A
; 119(12): e2115857119, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35298334
4.
o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.
J Enzyme Inhib Med Chem
; 39(1): 2313055, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38416868
5.
AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
J Biol Chem
; 298(10): 102453, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36063996
6.
Characterization and inhibition of inflammasome responses in severe and non-severe asthma.
Respir Res
; 24(1): 303, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38044426
7.
Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma.
J Allergy Clin Immunol
; 149(4): 1270-1280, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34678326
8.
Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection.
PLoS Pathog
; 16(8): e1008695, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32750090
9.
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Nat Chem Biol
; 15(6): 556-559, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31086327
10.
Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung.
J Immunol
; 203(10): 2724-2734, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586037
11.
NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients.
Brain
; 143(5): 1414-1430, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32282893
12.
The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins.
Glia
; 68(2): 407-421, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31596526
13.
Synthesis and evaluation of NLRP3-inhibitory sulfonylurea [11C]MCC950 in healthy animals.
Bioorg Med Chem Lett
; 30(12): 127186, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32312583
14.
Compromised NLRP3 and AIM2 inflammasome function in autoimmune NZB/W F1 mouse macrophages.
Immunol Cell Biol
; 97(1): 17-28, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30052286
15.
Quantitation of Purines from Pigeon Guano and Implications for Cryptococcus neoformans Survival During Infection.
Mycopathologia
; 184(2): 273-281, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30707338
16.
GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans.
J Biol Chem
; 292(7): 3049-3059, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062578
17.
Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
J Biol Chem
; 292(28): 11829-11839, 2017 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28559277
18.
PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome.
J Biol Chem
; 292(3): 826-836, 2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27913620
19.
An optimized whole blood assay measuring expression and activity of NLRP3, NLRC4 and AIM2 inflammasomes.
Clin Immunol
; 191: 100-109, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29183866
20.
Antimicrobial Octapeptin C4 Analogues Active against Cryptococcus Species.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29158283